Article
Bioenergetic and oxidative stress in neurodegenerative diseases.
Life sciences - 1 Jan 1995
Bowling A C, Beal M F
Abstract excerpt
Aging is a major risk factor for several common neurodegenerative diseases, including Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), and Huntington's disease (HD). Recent studies have implicated mitochondrial dysfunction and oxidative stress in the aging process and also in the pathogenesis of neurodegenerative diseases. In brain and other tissues, aging is associated...
Topics
- Aging
- Alzheimer Disease
- Amyotrophic Lateral Sclerosis
- Animals
- DNA, Mitochondrial
- Energy Metabolism
- Humans
- Huntington Disease
- Mitochondria
- Mutation
- Nervous System Diseases
- Oxidative Stress
