Article
Immunization against turkey coryza by colonization with mutants of Alcaligenes faecalis.
Avian diseases - 1 Jan 2000
Burke D S, Jensen M M
Abstract excerpt
Temperature-sensitive mutants of Alcaligenes faecalis that exhibited reduced growth at 42 C but grew well at 30 C were induced by N-methyl-N'-nitro-N-nitrosoguanidine. Four of the 5 mutants that were studied readily colonized the nasal mucosa of turkeys when given intranasally or in drinking water. Several mutants caused no signs of coryza or depression and produced minimal colonization of the trachea....
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