Article
4-Chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethylbiphenyl (4HMB): reverse mutation tests with Salmonella typhimurium.
Mutation research - 1 Jan 2000
Ladner A
Abstract excerpt
In this study 4CMB was shown to be a strong, direct-acting, mutagen for S. typhimurium strains TA1538, TA1537, TA98 and TA100. However, for strain TA1535 the compound was only weakly mutagenic. No conclusive evidence of mutagenic activity was seen in tests with BC or 4HMB.
Topics
- Benzyl Compounds
- Biphenyl Compounds
- Mutagenicity Tests
- Mutagens
- Mutation
- Salmonella typhimurium
- Species Specificity
- Structure-Activity Relationship