Article
Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma.
Nature - 1 Jan 2000
Godbout R, Dryja T P, Squire J, Gallie B L, Phillips R A
Abstract excerpt
Through family studies and analysis of patients with congenital chromosome abnormalities, the germ-line mutation responsible for the hereditary form of the eye tumour, retinoblastoma, has been assigned to the q14 region on chromosome 13 and closely linked to an enzyme called esterase D (ESD). Knu...
Topics
- Cell Line
- Chromosome Aberrations
- Chromosome Banding
- Chromosome Disorders
- Chromosomes, Human, 13-15
- Eye Neoplasms
- Functional Laterality
- Humans
- Karyotyping
- Mutation
- Oncogenes
- Retinoblastoma