Article
Ferrara beta 0 thalassaemia caused by the beta 39 nonsense mutation.
Nature - 1 Jan 2000
Pirastu M, del Senno L, Conconi F, Vullo C, Kan Y W
Abstract excerpt
Ferrara type of beta 0 thalassaemia has two unusual features: first, normal beta-globin chain synthesis is inducible either in cell-free systems prepared from patients' reticulocytes by adding supernatant factors from non-thalassaemic reticulocyte lysates or in heterologous cell-free translation of thalassaemic mRNA; second, beta-globin synthesis is inducible in patients in vivo after blood transfusion. We now...
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