Article
[Prenatal diagnosis of hemoglobinopathies in the 1st and 2nd pregnancy trimesters].
La Pediatria medica e chirurgica : Medical and surgical pediatrics - 1 Jan 2000
Ferrari M, Cantù Rajnoldi A, Cremonesi L, Donzelli C, Pietri S, Tedeschi S, Travi M, Nicolini U, Brambati B
Abstract excerpt
Fetal diagnosis of haemoglobinopathies, mainly thalassaemia, is widely used for the prevention of these diseases. Since 1975 fetal diagnosis has been carried out in the second trimester of pregnancy (18th - 22th week) on fetal blood samples obtained by fetoscopy or placentocentesis. The biochemical technique most commonly employed has been represented by carboxymethylcellulose chromatography and more recently in...
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