Article
Pharmacogenetic strategies for studying alcohol dependence.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2000
Crabbe J C
Abstract excerpt
The importance of genotypic differences in the determination of sensitivity to ethanol, tolerance development and physical dependence susceptibility is achieving ever greater recognition. It is now generally accepted by investigators studying the biochemical and physiological bases for alcoholism that genotype can influence all these different aspects of sensitivity to the effects of ethanol. Although there is...
Topics
- Alcoholism
- Animals
- Disease Models, Animal
- Environment
- Genetics, Behavioral
- Humans
- Mice
- Mice, Inbred Strains
- Pharmacogenetics
- Phenotype
- Rats
- Rats, Inbred Strains
