Article
[Genome instability and neoplasia].
TSitologiia i genetika - 1 Jan 2000
Shapot V S, Mironov N M
Abstract excerpt
Necessity of oncogene for the neoplastic cell transformation is substantiated. The oncogene may be introduced into the cell by a virus; be present in the cell from its formation but be repressed by products of regulatory genes; be arisen from separated DNA segments. The latter possibility is discussed in view of data on the presence of mobile elements and Sarc sequences in the cell genome.
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