Article
[Genome instability and neoplasia].
TSitologiia i genetika - 1 Jan 2000
Shapot V S, Mironov N M
Abstract excerpt
Necessity of oncogene for the neoplastic cell transformation is substantiated. The oncogene may be introduced into the cell by a virus; be present in the cell from its formation but be repressed by products of regulatory genes; be arisen from separated DNA segments. The latter possibility is discussed in view of data on the presence of mobile elements and Sarc sequences in the cell genome.
Topics
- Animals
- Carcinogens
- Cell Transformation, Neoplastic
- DNA Transposable Elements
- DNA, Neoplasm
- DNA, Viral
- Genes
- Genes, Regulator
- Molecular Weight
- Mutation
- Neoplasms, Experimental
- Oncogenic Viruses