Article
Gene structure of human cardiac hormone precursor, pronatriodilatin.
Nature - 1 Jan 2000
Nemer M, Chamberland M, Sirois D, Argentin S, Drouin J, Dixon R A, Zivin R A, Condra J H
Abstract excerpt
Atrial cardiocytes contain granules typical of protein-secreting cells, and atrial extracts are known to contain a powerful natriuretic and diuretic activity and to possess smooth muscle relaxant activity. A variety of active atrial peptides have been isolated, including a family of related peptides showing natriuretic, diuretic and smooth muscle relaxant activities in rat and human atria; these peptides were...
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