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Article

Enhanced killing effects of caffein post-treatment in ultraviolet-light irradiated mouse lymphoma cells: is cAMP a mediator of the effects?

Radiation medicine - 1 Jan 2000

Kuwashima Y, Miyachi Y, Okada S, Iio M, Nakamura N

Abstract excerpt

Effects of post-treatment with caffein, cyclic adenosine 3':5'-monophosphate (cAMP) and N6, O2-dibutyryl cAMP (dbcAMP) were investigated in ultraviolet light (UV)-irradiated mouse lymphoma L5178Y cells. Under conditions where UV or each chemical alone caused only slight cytotoxic effects, caffein post-treatment showed clear synergistic effects in cell killing but not for cAMP or dbcAMP. Subsequently, a mutant...

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PMID: 6093199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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