Enhanced killing effects of caffein post-treatment in ultraviolet-light irradiated mouse lymphoma cells: is cAMP a mediator of the effects?

Article

Enhanced killing effects of caffein post-treatment in ultraviolet-light irradiated mouse lymphoma cells: is cAMP a mediator of the effects?

Radiation medicine - 1 Jan 2000

Kuwashima Y, Miyachi Y, Okada S, Iio M, Nakamura N

Abstract excerpt

Effects of post-treatment with caffein, cyclic adenosine 3':5'-monophosphate (cAMP) and N6, O2-dibutyryl cAMP (dbcAMP) were investigated in ultraviolet light (UV)-irradiated mouse lymphoma L5178Y cells. Under conditions where UV or each chemical alone caused only slight cytotoxic effects, caffein...

Topics

Animals
Bucladesine
Caffeine
Cell Survival
Cells, Cultured
Clone Cells
Cyclic AMP
Leukemia L5178
Mice
Mutation
Neoplastic Stem Cells
Radiation Tolerance
Ultraviolet Rays

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