Emergence of a genetically distinct cluster of influenza A(H3N2) viruses within subclade J.2.2 associated with hospitalization during the 2024-2025 season in Auvergne-Rhône-Alpes, France.

doi:10.1099/mgen.0.001810

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Article

Emergence of a genetically distinct cluster of influenza A(H3N2) viruses within subclade J.2.2 associated with hospitalization during the 2024-2025 season in Auvergne-Rhône-Alpes, France.

Microbial genomics - 1 Sept 2026

Koumaty Lama, Dan Stéphanie, De Clercq Allan, Destras Grégory, Regue Hadrien, Oblette Antoine, Le Meur Adrien, Gaymard Alexandre, Escuret Vanessa, Bouscambert-Duchamp Maude, Chanard Emmanuel, Fabre Margaux, Vieillefond Vincent, Visseaux Benoit, Bal Antonin, Josset Laurence

Abstract excerpt

During the 2024-2025 influenza season in Auvergne-Rhône-Alpes, France, a genetically distinct cluster of A(H3N2) viruses within subclade J.2.2 was found to be significantly overrepresented in hospitalized patients compared with community patients. Circulating mainly in November and December 2024, this genetically distinct cluster harboured HA1:G62R and S145N mutations, both linked to immune escape, as well as...

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Topics

Humans
France
Influenza, Human
Influenza A Virus, H3N2 Subtype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Hospitalization

Seasons

Phylogeny

Genome, Viral

Hemagglutinin Glycoproteins, Influenza Virus

Whole Genome Sequencing

Mutation

Source

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Identifiers

PMID: 42771534
DOI: 10.1099/mgen.0.001810
PMCID: PMC13597097

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