Article
Molecular genetic diagnostics for ventricular arrhythmias and sudden cardiac death syndromes.
Herz - 1 Aug 2017
Stallmeyer B, Dittmann S, Seebohm G, Müller J, Schulze-Bahr E
Abstract excerpt
Inherited forms of ventricular arrhythmias are rare diseases, but a major cause for severe cardiac events, sudden unexplained death syndromes, and death in young adults, infants, and children. Each disorder is genetically heterogeneous (5-20 genes per disease) and molecular testing may include both core genes and less common disease genes as well. Owing to the rapid development and feasibility of sequencing...
Topics
- Adult
- Cause of Death
- Child
- DNA Mutational Analysis
- Death, Sudden, Cardiac
- Genetic Heterogeneity
- Genetic Testing
- Genome, Human
- Humans
- Infant
- Phenotype
- Sequence Analysis, DNA