HIV-1 transmitted drug resistance in Shanghai, 2018-2024: population mobility shapes cross-population TDR transmission dynamics.

doi:10.1080/22221751.2026.2731504

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Article

HIV-1 transmitted drug resistance in Shanghai, 2018-2024: population mobility shapes cross-population TDR transmission dynamics.

Emerging microbes & infections - 1 Dec 2026

Dong Yuan, Lin Qianru, Wang Xuqin, Liu Changhe, Yu Xiaolei, Tang Wenqi, Feng Wanqing, Lv Xiaoning, Han Yiqing, Yue Qing, Ning Zhen, Shen Xin, Chen Xin, Zhou Yanqiu, Chen Min, Wu Huanyu, Lin Yi

Abstract excerpt

Transmitted drug resistance (TDR) poses a growing challenge to HIV control, particularly in highly mobile urban settings with complex transmission dynamics. We analyzed HIV-1 pol sequences from 7,538 newly diagnosed, treatment-naïve individuals in Shanghai (2018-2024), integrating genotypic resistance testing, molecular transmission network analysis, and time-scaled discrete phylogeographic inference. Individuals...

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Topics

Humans
HIV-1
China
Drug Resistance, Viral
HIV Infections
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Adult

Anti-HIV Agents

Prevalence

Phylogeography

Phylogeny

Middle Aged

Genotype

Transients and Migrants

Source

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Identifiers

PMID: 42758933
DOI: 10.1080/22221751.2026.2731504
PMCID: PMC13592006

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