Stratifying the risk of anal high-grade squamous intraepithelial lesion among immunosuppressed women with genital HPV.

doi:10.3389/fimmu.2026.1936298

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Article

Stratifying the risk of anal high-grade squamous intraepithelial lesion among immunosuppressed women with genital HPV.

Frontiers in immunology - 1 Jan 2026

Matas Isabel, Pifarré Maria, Torné Aureli, Saco Adela, Darecka Katarzyna, Guerra Esther, Martí Cristina, Bruch Judit, Cardiel Ada, Rakislova Natalia, Marimon Lorena, Mayordomo-Bofill Isabet, Victoria Ingrid, Alós Silvia, Fusté Pere, Ordi Jaume, Del Pino Marta

Abstract excerpt

Introduction: Immunosuppressed women with human papillomavirus (HPV)-related genital disease are at increased risk of anal squamous cell carcinoma (ASCC), yet optimal risk stratification and screening strategies remain poorly defined. The aim of this study was to evaluate the prevalence of anal high-grade squamous intraepithelial lesions/anal intraepithelial neoplasia (HSIL/AIN), determine whether the anatomical...

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Topics

Humans
Female
Papillomavirus Infections
Squamous Intraepithelial Lesions
Anus Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Human Papillomavirus Viruses

Adult

Immunocompromised Host

Prevalence

Aged

Carcinoma, Squamous Cell

Risk Assessment

Papillomaviridae

Genotype

Risk Factors

Source

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Identifiers

PMID: 42741372
DOI: 10.3389/fimmu.2026.1936298
PMCID: PMC13572672

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