Familial short stature: genetic architecture, risk stratification, and precision management.

Abstract excerpt

Background: Familial short stature (FSS) has traditionally been considered a benign growth pattern characterized by short stature clustering within families and has often been regarded as a normal variant of growth. However, recent advances in genomic technologies have demonstrated that a subset of children presenting with an FSS phenotype harbor identifiable monogenic variants, particularly in genes involved in...

Topics

• Humans
• Growth Disorders
• Precision Medicine
• Risk Assessment
• Genetic Testing
• Dwarfism
• Human Growth Hormone
• Phenotype
• Body Height
• Genetic Predisposition to Disease