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Genomic Diversity of Vaginal Lactobacillus crispatus Prophages from South African Women.

Viruses - 30 Apr 2026

Jimoh Adijat Ozohu, Chicken Anika, Maust Brandon, Feng Colin, Rakoff-Nahoum Seth, Passmore Jo-Ann S, Kullin Brian R, Kraberger Simona, Hussain Fatima Aysha, Jaspan Heather B, Varsani Arvind, Happel Anna-Ursula

Abstract excerpt

Lactobacillus crispatus is widely associated with optimal sexual and reproductive health outcomes. While L. crispatus genomes commonly harbor prophages, little is known about their genomic diversity and potential inducibility by clinically relevant compounds. We induced and characterized four bacteriophages from four L. crispatus strains isolated from vaginal secretions of South African adolescents. Sequenced...

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Identifiers

PMID: 42198722
DOI: 10.3390/v18050519
PMCID: PMC13211564

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