Phenotyping Increased Urge to Defecate in Irritable Bowel Syndrome: Analysis of Symptom, Sensory, and Psychological Profiles.

doi:10.1002/ueg2.70287

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Article

Phenotyping Increased Urge to Defecate in Irritable Bowel Syndrome: Analysis of Symptom, Sensory, and Psychological Profiles.

United European gastroenterology journal - 1 Sept 2026

Groen Sylvester R, Vork Lisa, Weerts Zsa Zsa R M, Mujagić Zlatan, Conchillo José M, Masclee Ad A M, Jonkers Daisy M A E, Keszthelyi Daniel

Abstract excerpt

INTRODUCTION: Visceral hypersensitivity (VHS) is considered a hallmark of irritable bowel syndrome (IBS) characterized by altered thresholds for rectal pain and discomfort during rectal distention. Rectal distention can also elicit the urge to defecate, a normal physical sensation that is, reported more often in IBS and may involve mechanisms distinct from pain and discomfort. This study investigates clinical,...

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Topics

Adult
Female
Humans
Male
Middle Aged
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Defecation

Irritable Bowel Syndrome

Phenotype

Quality of Life

Rectum

Surveys and Questionnaires

Symptom Burden

Source

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Identifiers

PMID: 42689492
DOI: 10.1002/ueg2.70287
PMCID: PMC13539618

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