Flagellar toxicity: Flagellar synthesis is lytic for Bacillus subtilis in the absence of PBP1.

Abstract excerpt

Flagella are large transenvelope nanomachines but how they transit the peptidoglycan in gram-positive bacteria is poorly understood. A recent model suggested that flagellar basal bodies diffuse in the membrane and become captured at locations in the peptidoglycan with a pore diameter that could accommodate the axle-like flagellar rod. To test the role of pore size on flagellar assembly, cells were disrupted for...

Topics

• Bacillus subtilis
• Flagella
• Penicillin-Binding Proteins
• Peptidoglycan
• Bacterial Proteins
• Sigma Factor