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Article

Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity.

Clinical and translational medicine - 1 Sept 2026

McClellan Nicholas, Chen Li, Matossian Sophia, Rynda Aurora, Grant Kirsten, Janssen Erin, Kahlenberg J Michelle, Turnier Jessica L

Abstract excerpt

BACKGROUND: Nailfold capillaroscopy is a non-invasive method to visualize altered microcirculation in pediatric rheumatic disease, with potential to aid in diagnostic differentiation and disease monitoring. We used nailfold video capillaroscopy (NVC) and machine learning to identify patterns of capillaroscopic features in juvenile dermatomyositis (JDM) and associations of capillaroscopic features with clinical...

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Topics

Humans
Female
Male
Child
Microscopic Angioscopy
Adolescent

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Dermatomyositis

Phenotype

Capillaries

Nails

Myositis

Cluster Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 42681940
DOI: 10.1002/ctm2.70789
PMCID: PMC13535121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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