Successful Control of Late-Onset Nephrotic Syndrome in FN1-Associated Fibronectin Glomerulopathy: A 17-Year Clinical Course.

doi:10.1111/nep.70273

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Article

Successful Control of Late-Onset Nephrotic Syndrome in FN1-Associated Fibronectin Glomerulopathy: A 17-Year Clinical Course.

Nephrology (Carlton, Vic.) - 1 Sept 2026

Kanazawa Nobuhiro, Iyoda Masayuki, Abe Kazuki, Suzuki Taihei, Shirai Yoko, Miura Kenichiro, Honda Kazuho, Honda Hirokazu

Abstract excerpt

Fibronectin glomerulopathy (FNG) is a rare renal disorder characterized by excessive glomerular fibronectin deposition, often associated with variants in the fibronectin 1 (FN1) gene. Clinically, FNG presents with proteinuria, hematuria, and hypertension, and may progress to end-stage kidney disease. However, its long-term clinical course and optimal management remain incompletely defined. We report a sporadic...

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Topics

Humans
Female
Nephrotic Syndrome
Fibronectins
Adult
Immunosuppressive Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cyclosporine

Prednisolone

Treatment Outcome

Time Factors

Mutation

Remission Induction

Genetic Predisposition to Disease

Glomerulonephritis, Membranoproliferative

Source

Open in PubMed Open full text

Identifiers

PMID: 42675453
DOI: 10.1111/nep.70273
PMCID: PMC13529923

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