Article
Phenotype-Dependent Effect of Bedtime Antihypertensive Dosing on Nocturnal Blood Pressure: A Meta-Analysis Guided by Non-Dipper Prevalence.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Aug 2026
Li Min, Zhou Zuoyi, Fan Fangfang, Ma Wei, Li Jianping, Zhang Yan
Abstract excerpt
Bedtime dosing of antihypertensive medications is associated with a reduction in nocturnal blood pressure (BP), but whether this effect is modified at the study level remains uncertain. We conducted an updated meta-analysis of randomized controlled trials comparing bedtime versus morning antihypertensive administration, evaluating the overall treatment effect and its potential modification by baseline non-dipper...
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