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Article

Familial acute necrotizing encephalopathy temporally associated with SARS-CoV-2 infection: Two case reports and literature review.

Medicine - 21 Aug 2026

Zhang Ning, Fan Yipan, Ge Weixing, Lin Zhao

Abstract excerpt

RATIONALE: Acute necrotizing encephalopathy (ANE) is a rare but life-threatening parainfectious encephalopathy characterized by rapid neurological deterioration following viral infections. Although most cases occur sporadically, familial clustering is uncommon and suggests the involvement of genetic susceptibility factors. The emergence of coronavirus disease 2019 (COVID-19) has broadened the spectrum of viral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42629733
DOI: 10.1097/MD.0000000000050329
PMCID: PMC13502870

Genes

RANBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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