Article
Multilocus basis of incipient reproductive isolation in hybridizing populations is revealed by pangenomic and epigenetic divergence.
Science advances - 21 Aug 2026
Ruggieri Angelo A, Cicconardi Francesco, Bellin Nicolò, Montgomery Stephen H, Mallet James, Van Belleghem Steven M, McMillan Owen W, Counterman Brian A, Papa Riccardo
Abstract excerpt
Incipient reproductive isolation in the presence of gene flow has traditionally been attributed to a small number of major-effect loci under strong selection. Here, using the Heliconius erato adaptive radiation, we apply a pangenome framework to examine how mutational divergence, regulatory variation, and structural variants contribute to genome-wide divergence. In contrast to earlier studies, our high-resolution...
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