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Article

Experimental Pain Phenotypes in Individuals With Symptomatic Knee Osteoarthritis: A Neural Network-Based Clustering Approach.

Pain research & management - 1 Jan 2026

Lee Chiyoung, Kim Yeri, Kim Seoyoung, Park Juyoung, Sun Xiaoxiao, Chen Chen X, Kwoh C Kent, Liu Shen, Ahn Dasol, Kim Heewon, Ahn Hyochol

Abstract excerpt

OBJECTIVE: Research has emphasized the "phenotyping" of knee osteoarthritis (OA) pain as a priority to effectively target therapies to individual patients. This study identified pain phenotypes based on experimental pain responses in patients with symptomatic knee OA using machine learning approaches and examined their associations with participant characteristics. METHODS: In this cross-sectional study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42605842
DOI: 10.1155/prm/5069475
PMCID: PMC13479352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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