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Article

Causal association between sleep phenotypes and susceptibility to childhood asthma: A two-sample Mendelian randomization study.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Aug 2026

Yin Li, Zhang Feifei, Li Fang, Gao Mimi, Liu Anna, Wang Xue

Abstract excerpt

OBJECTIVE: This study applied two-sample Mendelian randomization (MR) to elucidate causal relationships between sleep-related phenotypes and childhood asthma risk. METHODS: Instrumental variables for daytime napping, sleep disorders, chronotype, and fatigue were selected from European ancestry genome-wide association studies. Causal estimates were primarily derived using inverse-variance weighting (IVW),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42605205
DOI: 10.1111/pai.70446
PMCID: PMC13478767

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