Article
Penicillin-resistant Streptococcus dysgalactiae subsp. equisimilis and the association with penicillin-binding protein mutations: a population genotypic and phenotypic study.
Antimicrobial agents and chemotherapy - 2 Sept 2026
Xie Ouli, Tan Aimee, Nguyen Thanh Binh, Hayes Andrew J, Dotel Ravindra, Carter Glen, O'Sullivan Matthew V N, Bond Katherine, McDevitt Christopher A, Korman Tony M, Currie Bart J, Ascher David B, Tong Steven Y C, van Hal Sebastiaan J, Davies Mark R
Abstract excerpt
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is increasingly recognized as a cause of human disease. Despite decades of penicillin use, SDSE is near universally penicillin-susceptible. Here we report and characterize by whole genome sequencing (WGS) three penicillin-resistant SDSE isolates (minimum inhibitory concentration [MIC] ≥0.256 mg/L) isolated from blood and skin in an individual with recurrent...
Read the complete abstract on PubMedTopics
- Penicillin-Binding Proteins
- Microbial Sensitivity Tests
- Anti-Bacterial Agents
- Penicillin Resistance