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Article

Evolutionary and molecular characteristics of high-Shannon entropy codons in VP1 of Coxsackievirus A6.

The Journal of general virology - 1 Jul 2026

Mo Han, Li Hui, Yi Liu, Qian Ke, Lin Juan, Lin Ziqi, He Fenglan, Zhang Xian, Ni Xiansheng, Zhou Xianfeng

Abstract excerpt

Coxsackievirus A6 (CVA6) has emerged as a predominant global pathogen of hand, foot and mouth disease, yet its evolutionary and molecular characteristics remain poorly understood. This study integrated 10 year molecular surveillance data from central China (2013-2024) with global CVA6 sequences to analyse high-entropy codons in the VP1 capsid protein and their co-evolution patterns. Phylogenetic and Bayesian...

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Capsid Proteins
China
Codon
Enterovirus
Entropy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Evolution, Molecular

Hand, Foot and Mouth Disease

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PMID: 42524876
DOI: 10.1099/jgv.0.002306
PMCID: PMC13418908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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