Article
An emerging and expanding clade accounts for the persistent outbreak of Coxsackievirus A6-associated hand, foot, and mouth disease in China since 2013.
Virology - 1 May 2018
He Shuizhen, Chen Mengyuan, Wu Wenhui, Yan Qiang, Zhuo Zhihao, Su Xiaosong, Zhang Shiyin, Ge Shengxiang, Xia Ningshao
Abstract excerpt
Enterovirus (EV)-A71 and Coxsackievirus (CV)-A16 have historically been the major pathogens of hand, foot, and mouth disease (HMFD) in China; however, CV-A6， which had previously received little attention, became the predominant pathogen in 2013, and has remained one of the common pathogens since then. In this work, we conducted a molecular epidemiology study of CV-A6-associated HFMD in Xiamen from 2009 to 2015....
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