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Phylogenetic Analysis of the VP1 Coding Region of Coxsackievirus A6 Detected in Hand-foot-and-mouth Disease During Surveillance from 2019 to 2024 in Japan.

Japanese journal of infectious diseases - 23 Mar 2026

Tsukagoshi Hiroyuki, Nagashima Mami, Takahashi Kumiko, Mizuta Katsumi, Ikeda Tatsuya, Shimada Ryo, Kawase Akira, Shinomiya Hiroto, Okamoto-Nakagawa Reiko, Shirabe Komei, Kaburagi Yasuo, Ichikawa Hiroyuki, Taguchi Monami, Abe Sakurako, Saruki Nobuhiro

Abstract excerpt

Hand, foot, and mouth disease (HFMD) caused by enteroviruses is common in children. Recently, coxsackievirus A6 (CVA6) has been identified as a major causative agent. In this study, we conducted a phylogenetic analysis of a part of the VP1 coding region of 194 CVA6 strains detected directly in 767 nasopharyngeal swab or stool samples of HFMD patients in Japan from 2019 to 2024. The detected CVA6 strains were...

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PMID: 40738663
DOI: 10.7883/yoken.JJID.2025.039

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