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Article

Café-au-lait macules in a cohort of Greek children genetically diagnosed with neurofibromatosis type 1: Prognostic significance beyond their diagnostic relevance.

Dermatology online journal - 30 Jun 2026

Alexopoulos Alexios, Ntokos Dimitrios, Briana Despina, Pons Roser, Stefanaki Christina, Kontara Louiza, Kanaka-Gantenbein Christina, Nasi Lamprini

Abstract excerpt

Background: Café-au-lait macules (CALMs) are often the earliest visible sign of neurofibromatosis type 1 (NF1), a genetic disorder with marked clinical variability. Early characterization of CALM patterns may aid in anticipating systemic disease burden. Objective: To analyze the early appearance, anatomical distribution, and number of CALMs in children with genetically confirmed NF1 and explore associations with...

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PMID: 42522512
DOI: 10.25251/10.25251/t1jlta74

Genes

NF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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