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Article

Molecular screening strategies for NF1-like syndromes with café-au-lait macules (Review).

Molecular medicine reports - 1 Nov 2016

Zhang Jia, Li Ming, Yao Zhirong

Abstract excerpt

Multiple café-au-lait macules (CALM) are usually associated with neurofibromatosis type 1 (NF1), one of the most common hereditary disorders. However, a group of genetic disorders presenting with CALM have mutations that are involved in human skin pigmentation regulation signaling pathways, including KIT ligand/KIT proto‑oncogene receptor tyrosine kinase and Ras/mitogen‑activated protein kinase. These disorders,...

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Identifiers

PMID: 27666661
DOI: 10.3892/mmr.2016.5760
PMCID: PMC5112360

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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