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Article

Predicting neurofibromatosis type 1 risk among children with isolated café-au-lait macules.

Journal of the American Academy of Dermatology - 1 Jun 2017

Ben-Shachar Shay, Dubov Tom, Toledano-Alhadef Hagit, Mashiah Jacob, Sprecher Eli, Constantini Shlomi, Leshno Moshe, Messiaen Ludwine M

Abstract excerpt

BACKGROUND: Although isolated cafe-au-lait macules (CALMs) are a common skin finding, they are an early feature of neurofibromatosis type 1 (NF1). OBJECTIVE: We sought to develop an algorithm determining the risk of children with CALMs to have constitutional NF1. METHODS: We conducted a retrospective study of patients with isolated CALMs. Diagnosis of NF1 was based on detecting NF1 mutation in blood or fulfilling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28318682
DOI: 10.1016/j.jaad.2017.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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