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The Inflammaging-Redox-InflammamiR Axis in Metabolic Aging: From Diagnostic Clusters to Integrated Risk Phenotypes.

Biomolecules - 10 Jul 2026

Ablaikhanova Nurzhanyat, Okhas Ingkar, Bolatov Aidos, Mukhitdin Beibarys, Zhunusbayeva Zhazira, Assan Gulmira, Kulbayeva Marzhan, Tolebaeva Anar, Yessenbekova Arailym, Rusanova Iryna

Abstract excerpt

Age-associated metabolic dysfunction is commonly defined by abnormalities in adiposity, glucose regulation, lipid metabolism, and blood pressure. Although clinically useful, these criteria do not fully capture the biological heterogeneity that explains why older adults with similar metabolic profiles may follow divergent trajectories toward type 2 diabetes, cardiovascular disease, metabolic dysfunction-associated...

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PMID: 42509801
DOI: 10.3390/biom16071008
PMCID: PMC13406806

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