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Article

Risk Phenotyping Before Graft Implantation: FTIR Spectroscopy and Machine Learning for Complementary Risk Stratification in Kidney Transplantation.

Medical sciences (Basel, Switzerland) - 27 Jun 2026

Ramalhete Luis, Araújo Rúben, Vigia Emanuel, Vieira Miguel Bigotte, Ferreira Anibal, Calado Cecilia R C

Abstract excerpt

BACKGROUND: Rejection remains a major barrier to long-term kidney allograft survival, and pre-transplant risk stratification remains incomplete. This study evaluated whether pre-transplant serum Fourier-transform infrared (FTIR) spectra, analyzed using machine learning methods, could identify kidney transplant recipients at increased risk of subsequent biopsy-proven rejection. METHODS: In this retrospective...

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Identifiers

PMID: 42506321
DOI: 10.3390/medsci14030353
PMCID: PMC13413492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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