Article
Experimental evolution reveals genetic and transcriptomic mechanisms underlying benzalkonium chloride tolerance and fluoroquinolone cross-resistance in Listeria monocytogenes.
mSystems - 18 Aug 2026
Bechtel Tyler D, Hershelman Julia, Adeyanju Adenike, Rinker David C, Ghoshal Mrinalini, McLandsborough Lynne A, Gibbons John G
Abstract excerpt
Preventing Listeria monocytogenes persistence in food processing environments is challenged by tolerance to quaternary ammonium compound sanitizers such as benzalkonium chloride (BAC). To define the genetic and molecular routes to BAC tolerance and antibiotic cross-resistance, we performed an evolve-and-resequence experiment on three L. monocytogenes strains (three replicate lineages each) passaged under...
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