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Contribution of amino acid substitutions in CYP51A and CYP51B to pefurazoate resistance in Fusarium fujikuroi.

Pesticide biochemistry and physiology - 1 Aug 2026

Yu Min, Tsukamoto Aki, Sakahara Yuri, Sado Shota, Kamatari Yuji O, Matsumoto Junichi, Hori Takeshi, Shimizu Masafumi, Hieno Ayaka, Suga Haruhisa

Abstract excerpt

Rice bakanae disease, caused by the fungal pathogen Fusarium fujikuroi, results in significant yield reductions in global rice production. Pefurazoate, one of the sterol 14α-demethylase inhibitors (DMIs), has been used to control rice bakanae disease. However, pefurazoate-resistant isolates have also been reported in Japan. The F490V substitution in FfCYP51A or S312T/F511S substitutions in FfCYP51B were found in...

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PMID: 42493059
DOI: 10.1016/j.pestbp.2026.107248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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