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Article

Genetic predisposition in gynecologic cancers: From knowledge to clinical management.

Hellenic journal of nuclear medicine - 1 Jan 2026

Satra Maria

Abstract excerpt

Genetic predisposition contributes significantly to the development of specific gynecologic cancers, particularly ovarian and endometrial malignancies. Germline pathogenic variants in BRCA1 and BRCA2 genes account for a considerable proportion of hereditary ovarian cancer cases, while mismatch repair gene alterations underlie Lynch syndrome, strongly associated with endometrial cancer. Current international...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42472326

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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