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Article

Investigation of ACE gene polymorphism and serum ACE activity in relation to alopecia areata among Iraqi patients.

Human immunology - 1 Sept 2026

Dhahir Dalya Jamal, Mohammed Mohammed A, Al-Halbosiy Mohammad M F

Abstract excerpt

BACKGROUND: Alopecia areata (AA) is a multifactorial disorder with immune dysregulation and genetic susceptibility, affecting 0.5-2% globally. OBJECTIVE: This study investigated angiotensin converting enzyme (ACE) gene insertion /deletion (I/D) polymorphism and serum ACE activity in Iraqi AA patients and their association with inflammatory cytokines (interleukin [IL]-17) and nutritional markers to understand...

Read the complete abstract on PubMed

Topics

Humans
Female
Male
Peptidyl-Dipeptidase A
Iraq
Alopecia Areata
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Case-Control Studies

Genetic Predisposition to Disease

Interleukin-17

Genotype

Young Adult

Adolescent

Polymorphism, Genetic

Biomarkers

Middle Aged

Gene Frequency

Source

Identifiers

PMID: 42470820
DOI: 10.1016/j.humimm.2026.111807

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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