Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Mottling Phenotype in Chickens Shows Genetic Heterogeneity and Is Caused by Mutations at the EDNRB2 Locus.

Animal genetics - 1 Aug 2026

Li Jingyi, Bortoluzzi Chiara, Hodge McKaela, Bed'hom Bertrand, Guo Yifan, Davis Brian, Dorshorst Benjamin, Siegel Paul, Gourichon David, Tixier-Boichard Michèle, Andersson Leif

Abstract excerpt

Mottling is a widespread intra-feather pattern present in many breeds of domestic chickens worldwide and inherited as an autosomal recessive trait. An amino acid substitution Arg332His in the EDNRB2 gene was previously reported as responsible for the mottling phenotype in several Japanese breeds of chickens. Here, we show that this substitution is not causal for mottling in Mottled Houdan chicken, a breed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chickens
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Mutation, Missense

Share to Phenotype

Share to Pigmentation

Share to Polymorphism, Single Nucleotide

Share to Receptor, Endothelin B

Source

Open in PubMed Open full text

Identifiers

PMID: 42466956
DOI: 10.1002/age.70168
PMCID: PMC13378286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Mottling Phenotype in Chickens Shows Genetic Heterogeneity and Is Caused by Mutations at the EDNRB2 Locus.PMID 42466956Read ↗

Whole-genome resequencing reveals loci with allelic transmission ratio distortion in F1 chicken population.Semantic proximity Read ↗

A 2-bp deletion in intron 1 of TMEM182 is associated with TMEM182 mRNA expression and chicken body weight.Semantic proximity Read ↗

Structural variation and eQTL analysis in two experimental populations of chickens divergently selected for feather-pecking behavior.Semantic proximity Read ↗

Alternative splicing variants and DNA methylation status of BDNF in inbred chicken lines.Semantic proximity Read ↗

An association between genetic variation in the roundabout, axon guidance receptor, homolog 2 gene and immunity traits in chickens.Semantic proximity Read ↗

Study on heteroplasmic variation and the effect of chicken mitochondrial ND2.Semantic proximity Read ↗

Enhanced Expression of Serotonin Receptor 5-Hydroxytryptamine 2C is Associated with Increased Feather Damage in Dongxiang Blue-Shelled Layers.Semantic proximity Read ↗

A Complex Structural Variation on Chromosome 27 Leads to the Ectopic Expression of HOXB8 and the Muffs and Beard Phenotype in Chickens.Semantic proximity Read ↗

Neurexophilin 1 gene polymorphism in chickens and its variation among species.Semantic proximity Read ↗

A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chicken.Semantic proximity Read ↗

Gene expression patterns of chicken neuregulin 3 in association with copy number variation and frameshift deletion.Semantic proximity Read ↗

Endothelin receptor B2 (EDNRB2) is responsible for the tyrosinase-independent recessive white (mo(w) ) and mottled (mo) plumage phenotypes in the chicken.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.