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Article

A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chicken.

PLoS genetics - 1 Dec 2011

Dorshorst Ben, Molin Anna-Maja, Rubin Carl-Johan, Johansson Anna M, Strömstedt Lina, Pham Manh-Hung, Chen Chih-Feng, Hallböök Finn, Ashwell Chris, Andersson Leif

Abstract excerpt

Dermal hyperpigmentation or Fibromelanosis (FM) is one of the few examples of skin pigmentation phenotypes in the chicken, where most other pigmentation variants influence feather color and patterning. The Silkie chicken is the most widespread and well-studied breed displaying this phenotype. The presence of the dominant FM allele results in extensive pigmentation of the dermal layer of skin and the majority of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22216010
DOI: 10.1371/journal.pgen.1002412
PMCID: PMC3245302

Genes

EDN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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