Ventricular Arrhythmia Ablation in Inherited Cardiomyopathy: Phenotype Variability and Outcomes Based on Functional Genotypes.

doi:10.1161/JAHA.126.050508

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Article

Ventricular Arrhythmia Ablation in Inherited Cardiomyopathy: Phenotype Variability and Outcomes Based on Functional Genotypes.

Journal of the American Heart Association - 21 Jul 2026

Afzalian Arian, Oraii Alireza, Markman Timothy M, Reza Nosheen, Deo Rajat, Owens Anjali, Enriquez Andres, Hanumanthu Balaram Krishna J, Hyman Matthew C, Mirwais Maiwand, Guandalini Gustavo, See Vincent Y, Schaller Robert D, Supple Gregory E, Riley Michael P, Nazarian Saman, Lin David, Garcia Fermin C, Dixit Sanjay, Epstein Andrew E, Frankel David S, Callans David J, Marchlinski Francis E, Shivamurthy Poojita

Abstract excerpt

BACKGROUND: Inherited cardiomyopathies cause ventricular tachycardia (VT) and heart failure, yet genotype-based substrate characterization is limited. METHODS: Patients with inherited cardiomyopathy undergoing VT (n=80) or premature ventricular complex (n=25) ablation between 2010 and 2024 were evaluated for arrhythmia substrate, ablation, and heart failure outcomes. RESULTS: Among 105 patients, the median age...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42466487
DOI: 10.1161/JAHA.126.050508
PMCID: PMC13477399

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DSP
LMNA

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