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Harnessing genetic, chemical, and transcriptomic analyses guided the selection of Cistus creticus subsp. creticus genotypes rich in labdane-type diterpenes.

Planta - 15 Jul 2026

Kostas Stefanos, Ntoanidou Symela, Bazakos Christos, Sarrou Eirini, Rafailidou Nausica, Papanikolaou Antigoni, Makris Antonios, Kotoula Aikaterini-Angeliki, Hatziloukas Efstathios, Economou Athanasios, Kanellis Angelos K

Abstract excerpt

MAIN CONCLUSION: The present study connects the genetic diversity of Cistus creticus to its chemical profile, identifying elite genotypes and key biosynthetic genes for enhancing the production of valuable labdane diterpenes. Cistus creticus, a Mediterranean shrub, is known for its resin ladano, which is rich in pharmacologically active labdane-related diterpenes (LRDs). However, the genetic and molecular basis...

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Diterpenes
Gene Expression Profiling
Gene Expression Regulation, Plant
Genetic Variation

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PMID: 42455372
DOI: 10.1007/s00425-026-05072-1
PMCID: PMC13372853

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