Article
Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast.
Scientific reports - 18 Aug 2017
Ignea Codruta, Athanasakoglou Anastasia, Andreadelli Aggeliki, Apostolaki Maria, Iakovides Minas, Stephanou Euripides G, Makris Antonios M, Kampranis Sotirios C
Abstract excerpt
Plants synthesize numerous specialized metabolites (also termed natural products) to mediate dynamic interactions with their surroundings. The complexity of plant specialized metabolism is the result of an inherent biosynthetic plasticity rooted in the substrate and product promiscuity of the enzymes involved. The pathway of carnosic acid-related diterpenes in rosemary and sage involves promiscuous cytochrome...
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