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Article

Molecular Feasibility of Gene Sequencing on Lymph Node Fine-Needle Cytology Samples of Non-Hodgkin Lymphoma.

International journal of molecular sciences - 2 Jul 2026

D'Ardia Angela, Maffei Elisabetta, Gaeta Sara, Infante Teresa, Giudice Valentina, Sabbatino Francesco, Di Filippo Anna, Picardi Marco, Zeppa Pio, Caputo Alessandro

Abstract excerpt

Non-Hodgkin lymphomas (NHL) are lymphoproliferative neoplasms with a heterogenous genetic landscape that require multiple assays to be characterized. Cytological samples are frequently utilized in the diagnosis of NHL. An RNA-based assay was utilized to detect translocations and identify mutations in fine-needle aspiration cytology (FNAC) samples of NHL. Fragmentation index and RNA concentration were evaluated in...

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Topics

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Share to Biopsy, Fine-Needle
Share to BCL6 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to FOXP1 gene

Share to High-Throughput Nucleotide Sequencing

Share to Lymph Nodes

Share to Lymphoma, Non-Hodgkin

Share to Mutation

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 42450228
DOI: 10.3390/ijms27135962
PMCID: PMC13362168

Genes

BCL6
IGH
BCL2
CCND1
EIF4A2
EIF4E3
FOXP1
FUT8
MYD88
TBL1XR1
TP53
TP63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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