Article
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.
Haematologica - 1 Sept 2016
Rosenquist Richard, Rosenwald Andreas, Du Ming-Qing, Gaidano Gianluca, Groenen Patricia, Wotherspoon Andrew, Ghia Paolo, Gaulard Philippe, Campo Elias, Stamatopoulos Kostas
Abstract excerpt
Similar to the inherent clinical heterogeneity of most, if not all, lymphoma entities, the genetic landscape of these tumors is markedly complex in the majority of cases, with a rapidly growing list of recurrently mutated genes discovered in recent years by next-generation sequencing technology. Whilst a few genes have been implied to have diagnostic, prognostic and even predictive impact, most gene mutations...
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