Biobank-scale genotype similarity search and dynamic patient-matched cohort creation with GenoSiS.

Abstract excerpt

Many patients do not experience optimal benefits from medical advances because clinical research does not adequately represent them. Although the diversity of biomedical research cohorts is improving, ensuring that individual patients are adequately represented remains challenging. We propose a new approach, GenoSiS, which leverages machine learning-based similarity search to dynamically find patient-matched...

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