Genetic variants modulate the effects of EGCG on adiposity and insulinemia in Diversity Outbred mice.

Abstract excerpt

Dietary polyphenols have been studied for their potential to mitigate cardiometabolic disease risk; however, their metabolic effects show significant interindividual variability. While factors such as sex, age, health status or polyphenol metabolism have been proposed to explain this heterogeneity, studies on host genetic variability are very limited. Moreover, reliance on a genetically inbred mouse model limits...

Topics

Join the communities discussing this publication.

• Adiposity
• Blood Glucose
• Catechin
• Diet, High-Fat
• Genetic Variation