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Article

Heritability of Triglyceride-Glucose Index in Middle-Aged and Older Chinese Twins: Overall Estimates and Sex-Stratified Analysis.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2026

Hu Xiaolin, Kong Weizheng, Peng Yurun, Tian Ruiyuan, Zhang Yi, Zhang Kai, Wang Weijing, Tian Xiaocao, Zhang Dongfeng, Fan Junning

Abstract excerpt

The triglyceride-glucose (TyG) index is a reliable composite marker of insulin resistance, which holds important clinical significance. Existing studies have predominantly focused on identifying TyG index-related genetic loci and single-nucleotide polymorphism (SNP)-based polygenic risk scores, however, the overall contribution of genetic factors to TyG index variation at the population level is still unclear. To...

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PMID: 42421488
DOI: 10.1017/thg.2026.10088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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