Evaluation and analysis of multidrug resistance- and hypervirulence-associated genes in carbapenem-resistant Pseudomonas aeruginosa strains among children in an area of China for five consecutive years

Abstract excerpt

Introduction Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a growing threat. It is urgent to investigate the multidrug resistance and high virulence of CRPA to provide a basis for infection control and rational use of antibiotics. Methods A retrospective study of 56 nonduplicated CRPA isolates was conducted. Results CRPA mainly came from the intensive care unit (ICU) and was mostly isolated from sputum...