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Revisiting the Palimpsest: Exploring the Interaction of the Variance and Structure of Developmental Determinants of Phenotypic Covariance.

Integrative and comparative biology - 12 Jan 2026

Andrade Fernando, Aponte J David, Young Nathan M, Marcucio Ralph S, Hallgrímsson Benedikt

Abstract excerpt

The analysis of patterns of trait covariance is of tremendous importance in the study of evolution and development as well as in quantitative genetics. Multivariate quantitative genetics and morphological integration were combined in the 1980s under the latent variable model for integration developed by Wagner and Cheverud. The palimpsest framework builds on this model. Based on a definition of integration as...

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PMID: 42411837
DOI: 10.1093/icb/icag111
PMCID: PMC13446123

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